The Science Behind
Your Confidence
Founded in 1998 and headquartered in St. Louis, Missouri, Meramec Bio Eval Center has spent over two decades building one of the most trusted contract testing operations in the United States. We deliver rigorous, GLP-compliant safety and efficacy data that stands up to regulatory scrutiny worldwide.
A Quarter Century of Scientific Rigor
Meramec Bio Eval Center was established in 1998 by a team of toxicologists and veterinary scientists who recognized the need for a mid-size contract laboratory that could deliver the scientific depth of a large CRO with the responsiveness and client partnership of a specialized facility.
Today, from our 12,000-square-foot campus in Missouri, we serve over 200 pharmaceutical, veterinary, cosmetic, and agrochemical companies across North America, Europe, and Asia-Pacific. Our studies have supported product registrations in more than 30 countries.
Science in service of safety
Every study we conduct ultimately protects human health, animal welfare, or environmental integrity. That responsibility guides every protocol we design and every data point we report.
Scientific Integrity
Data quality is non-negotiable. Every study follows validated protocols with full traceability, peer-reviewed pathology, and independent QA oversight. We report what the science shows.
Animal Welfare
We maintain USDA-registered facilities with IACUC oversight and enrichment programs that exceed regulatory minimums. The 3Rs framework — Replacement, Reduction, Refinement — is embedded in every study design.
Regulatory Excellence
Our team maintains active relationships with FDA, USDA, EPA, and international regulatory bodies. We design studies that anticipate reviewer expectations and minimize information requests.
Client Partnership
We assign a dedicated study director and project manager to every program. Real-time study access, proactive communication, and scientific consultation throughout the study lifecycle.
Regulatory Standards We Uphold
Our facility and study operations are designed to meet or exceed the requirements of every major regulatory framework. Studies conducted at Meramec are accepted by authorities worldwide.
Good Laboratory Practice
Full GLP compliance per FDA 21 CFR Part 58 and OECD Principles. Independent QA oversight for every study.
USDA Registered
Animal Welfare Act compliance with IACUC oversight and regular USDA/APHIS inspections.
FDA Compliance
Studies designed per FDA guidance for CDER, CBER, CVM, and CDRH submissions.
EPA FIFRA/TSCA
Agrochemical and industrial chemical safety evaluation. 40 CFR Part 160 GLP adherence.
OECD Test Guidelines
Internationally accepted test guidelines enabling mutual data acceptance across 30+ countries.
ICH Harmonized
Pharmaceutical development standards S1–S10 supporting global regulatory submissions.
Purpose-Built for Regulatory Science
Missouri Campus
Our 12,000-square-foot research campus in St. Louis, Missouri, was purpose-built for GLP-compliant contract testing. The facility includes dedicated housing for five species, HEPA-filtered barrier rooms, a BSL-2 large-animal containment unit, and a USDA-registered poultry research facility.
Key facility features include climate-controlled animal housing with automated environmental monitoring, a full-service clinical pathology and histopathology laboratory, necropsy and tissue processing suites, dedicated formulation and dose preparation areas, and secure archives with electronic data management.
Our central Missouri location provides logistical advantages for study material and specimen shipping, with direct access to major freight carriers and next-day service to both coasts.
Small Animal Wing
Purpose-bred canine and feline colonies with individual housing, enrichment programs, and dedicated veterinary staff. Rodent facility with barrier-level biosecurity and automated rack systems.
Large Animal Facility
200-head cattle capacity with indoor/outdoor housing, BSL-2 containment for challenge studies, and specialized handling equipment. Adjacent poultry facility supporting broiler and layer research.
Analytical Laboratory
On-site clinical pathology, histopathology, and bioanalytical capabilities. HPLC, LC-MS/MS, and automated hematology and chemistry analyzers for real-time study monitoring and rapid data turnaround.